VINTIX

Meridia, Sibutramine HCL, Reductil, Raductil, Ectiva, Obestat, Sibumine, Aderan, Sibutral, Sibutramina, Sibutraminum, Leptos

VINTIX is a brand name of Sibutramine.

VINTIX Review

VINTIX is used along with a low-calorie diet to help people with obesity lose weight. Reducing excess weight helps to prevent or control complications such as heart disease, diabetes, and joint pain. VINTIX works by affecting the area in your brain that controls hunger, providing you with a sense of fullness and satisfaction.

Who Should Take VINTIX

VINTIX is recommended for:

• Overweight people with an initial Body Mass Index (BMI) of 30 or higher
or
• Overweight people with a BMI of 27 or higher if they have medical risk factors such as high blood pressure, diabetes, or high cholesterol.

BMI is an indicator of total body fat, which can be related to the risk of certain diseases and premature death. Your doctor can tell you if your BMI meets these criteria and if VINTIX might be right for you.

How VINTIX Works

VINTIX works by acting on the appetite control center in the brain. Studies have shown that using VINTIX, along with a reduced-calorie diet and exercise, helped patients lose weight and maintain weight loss for up to two years.

The active ingredient in VINTIX, sibutramine, works in the area of the brain that signals the sense of fullness (satiety).

VINTIX blocks the re-uptake of the brain chemicals (serotonin and norepinephrine) which help regulate the sense of fullness. Fullness is your signal to stop eating. Having a sense of fullness, or satiety, means you may feel satisfied with less food.

Sibutramine should be used in conjunction with a reduced calorie diet. Always consult your physician before beginning any diet or exercise program.

VINTIX - Clinical Experience

Sibutramine, the active ingredient in VINTIX, has been extensively studied throughout the world. It has been studied in more than 100 clinical trials involving more than 12,000 patients. Approximately 14 million patients in more than 75 countries have used sibutramine for the treatment of obesity since it was approved in 1997. In studies, sibutramine in combination with diet and exercise was effective in producing and maintaining significant weight loss in the majority of obese patients compared to diet and exercise alone.

We all want quick results. But when it comes to losing weight, patience really is a virtue–losing weight gradually (one to two pounds per week), while changing your eating habits, gives you a much better chance of keeping it off. Every person will respond differently to VINTIX when used as part of a comprehensive weight-loss program. You may be able to lose four or more pounds of body weight in the first month you take VINTIX. If you find that you do not lose at least four pounds during the first month, you should notify your doctor so he or she can re-evaluate your therapy. Your doctor may wish to change your dose of VINTIX.

Most people who lose weight on VINTIX plus diet and exercise lose it in the first six months of treatment. A scientific study that lasted two years showed that over 40% of the people who lost weight in the first six months and remained on VINTIX therapy plus diet and exercise maintained their weight loss.

Most importantly though, be patient. Remember when you lose weight quickly, you often gain it back. Losing weight slowly, while changing your eating habits, gives you a much better chance of keeping it off.

How to use VINTIX Oral

Take VINTIX by mouth, usually once daily with or without food, or as directed by your doctor. Use VINTIX regularly in order to get the most benefit from it. Remember to use it at the same time each day. Dosage is based on your medical condition and response to therapy.

Do not increase your dose, take it more frequently, or use it for a longer period of time than prescribed. Do not suddenly stop using VINTIX without your doctor's approval. Your dose may need to be gradually reduced, especially if you have been taking this medication for a long time. Consult your doctor or pharmacist for more details.

VINTIX - Pharmacological aspects

Sibutramine is a neurotransmitter reuptake inhibitor that helps enhance satiety by inhibiting the reuptake of serotonin (by 53%), norepinephrine (by 54%), and dopamine (by 16%). Despite its actions upon the aforementioned neurotransmitters, sibutramine failed to demonstrate antidepressant properties in animal studies. It was approved by the U.S. Food and Drug Administration (FDA) in November 1997 for the treatment of obesity.

Sibutramine acts by increasing serotonin and norepinephrine levels in the brain. The serotonergic action, in particular, is thought to influence appetite.

VINTIX Side Effects

VINTIX, like all medications, may cause side effects. In studies the most common side effects were:

• headache
• dry mouth
• constipation
• anorexia
• and insomnia (inability to fall asleep)

Other side effects that may occur include:

• increased sweating
• an increase in blood pressure
• increase in heart rate

These side effects are generally mild, and have usually not caused people to stop taking VINTIX. If you develop a symptom that you think might be a side effect, stop taking VINTIX and notify your doctor immediately so he or she can advise you on what to do.

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