Weight loss pill

FDA-Approved Prescription Weight-loss Medications

These Weight loss pills are typically subjected to a range of clinical tests to prove their effectiveness for weight reduction and to monitor side effects and health risks.

1. Approved for long-term use:
   Orlistat (Trade Name Xenical);
   Sibutramine (Trade Names: Meridia, Vintix, Ectiva, Reductil, Raductil, Obestat).
2. Approved for short-term use:
   Diethylpropion (Trade Names: Tenuate, Tenuate dospan, Tenuate retard, Regenon, Neobes);
   Phentermine (Trade Names: Adipex-P, Fastin, Ionamin, Oby-trim, Pro-Fast, Zantryl);
   Phendimetrazine (Trade Names: Bontril, Plegine, Prelu-2, X-Trozine, Adipost).

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Weight loss pills types

• Appetite suppressants.
  Most available weight-loss medications approved by the Food and Drug Administration (FDA) are appetite-suppressant medications. Appetite-suppressant medications promote weight loss by decreasing appetite or increasing the feeling of being full. These medications make you feel less hungry by increasing one or more brain chemicals that affect mood and appetite. Phentermine and sibutramine are the most commonly prescribed appetite-suppressants in the U.S.
• Lipase inhibitors.
  One drug works in a different way. Orlistat works by reducing the body’s ability to absorb dietary fat by about one third. It does this by blocking the enzyme lipase, which is responsible for breaking down dietary fat. When fat is not broken down, the body cannot absorb it, so fewer calories are taken in.
• Drug combinations.
  The combined drug treatment using fenfluramine and phentermine (“fen/phen”) is no longer available due to the withdrawal of fenfluramine from the market after some patients experienced serious heart and lung disorders. Little information is available about the safety or effectiveness of other drug combinations for weight loss, including fluoxetine/phentermine, phendimetrazine/phentermine, orlistat/sibutramine, herbal combinations, or others.
• Drugs in development.
  Many medications are being tested as potential treatments for obesity. Two are being studied with patients in clinical trials. Rimonabant affects brain chemicals and ciliary neurotrophic factor affects hormones to control appetite

See also: Weight loss.